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Can iron deficiency cause dry lips?

Dry, cracked lips are a common problem that most people experience at some point. While dry lips may seem like just a cosmetic nuisance, they can be symptomatic of an underlying health condition. One potential cause is iron deficiency or anemia. Iron is an essential mineral that has many important functions in the body. When iron levels are low, it can manifest in various symptoms, including potentially dry lips. In this article, we’ll explore the link between iron deficiency and dry lips and provide an overview of some key points:

  • What is iron deficiency?
  • What causes iron deficiency?
  • Signs and symptoms of iron deficiency
  • How iron deficiency can lead to dry lips
  • Other causes of dry lips
  • Treatment for dry lips from iron deficiency
  • Prevention of dry lips from low iron

Understanding the connection between low iron stores and dry, cracked lips can help identify an underlying problem and guide treatment. If iron deficiency is the culprit, addressing this nutritional deficiency can often resolve symptoms.

What is Iron Deficiency?

Iron deficiency occurs when the body does not have enough of the mineral iron. This important micronutrient has several key functions:

  • Formation of hemoglobin and myoglobin, which carry oxygen throughout the body
  • Enzyme systems that produce energy and build proteins
  • Supporting a healthy immune system

When the body is low in iron, it cannot properly carry out these critical processes. Iron deficiency ranges from depleted iron stores without functional impacts all the way to full-blown iron deficiency anemia.

The stages of iron deficiency are:

  1. Iron depletion – iron stores are decreased but levels are still sufficient
  2. Early functional iron deficiency- iron begins to impact enzymes and proteins
  3. Iron deficiency anemia – hemoglobin levels drop, impacting oxygen transport

Iron deficiency anemia is the most severe form and occurs when lack of iron significantly decreases red blood cell production.

Prevalence of Iron Deficiency

Iron deficiency is very common worldwide, estimated to impact:

  • Up to 80% of people in developing countries
  • 2-5% of adults in developed countries like the United States
  • 7-12% of adolescent girls and women of childbearing age in developed countries

Young children and pregnant women also have higher requirements for iron, increasing risk of deficiency. Those with poor dietary intake of iron rich foods, malabsorption disorders, or chronic blood loss are also at greater risk of low iron levels.

What Causes Iron Deficiency?

There are several potential causes for developing an iron deficiency:

Inadequate Dietary Iron Intake

The main source of iron is food, particularly:

  • Red meat
  • Poultry
  • Seafood
  • Iron-fortified cereals and breads
  • Iron-rich plant foods like beans, spinach, and raisins

Those who eat a very restricted diet lacking these iron-rich foods can over time develop iron deficiency. This explains why rates are higher in developing countries where food variety and iron intake is limited.

Blood Loss

Losing blood through internal or external bleeding can deplete iron stores over time. In adults, common sources of blood loss include:

  • Ulcers
  • Regular use of aspirin or NSAID pain relievers
  • Frequent blood donations

In premenopausal women, heavy menstrual periods raise the risk of iron deficiency. Blood loss during childbirth can also contribute to iron deficiency.

Pregnancy and Growth

Pregnancy significantly increases iron needs to support fetal development and expansion of maternal blood volume. Infants and young children also require ample iron during periods of rapid growth and development. When iron intake is insufficient, deficiency can occur.


Certain digestive disorders make it difficult to absorb dietary iron properly. This includes:

  • Celiac disease
  • Inflammatory bowel disease
  • Chronic diarrhea
  • Intestinal surgery
  • Helicobacter pylori infection

Even if iron intake is adequate, impaired absorption can lead to low iron levels over time.

Other Causes

Less common causes of iron deficiency include bleeding disorders like hemophilia, cancer, liver disease, andautoimmune disorders. Kidney failure can also impact iron status and lead to anemia.

Signs and Symptoms of Iron Deficiency

In the early stages, iron deficiency may have no noticeable symptoms. As it progresses to iron deficiency anemia, signs and symptoms develop including:

  • Fatigue, weakness, pale skin
  • Rapid heartbeat
  • Shortness of breath
  • Headache, dizziness
  • Swollen or sore tongue
  • Cracks or sores at the corners of the mouth
  • Restless legs syndrome
  • Brittle nails
  • Poor appetite
  • Difficulty regulating body temperature
  • Brain fog, impaired concentration and memory

For reasons not entirely understood, iron deficiency seems particularly prone to causing symptoms in the lips, mouth, and tongue. This includes soreness, swelling, redness, and dry cracked lips.

How Can Iron Deficiency Lead to Dry Lips?

While all the mechanisms are still being elucidated, a few key reasons low iron levels are believed to cause dry, cracked lips include:

Reduced Blood Flow

With anemia, transport of oxygen through the blood is impaired. This can reduce peripheral blood circulation, including blood flow to the lips. Poor circulation and oxygen delivery to lip tissue can interfere with normal moisture and tone.

Nutrient Deficiencies

Iron is needed to produce hemoglobin, but it also supports many enzymes that drive energy production and protein synthesis. Deficiencies in iron can therefore lead to deficiencies in other nutrients needed for healthy skin and lips.


Research indicates iron deficiency can trigger inflammatory responses in the body. Inflammation is linked to faster cell turnover and exfoliation, which may worsen dryness and cracking of the lips.

Candida Overgrowth

There is some evidence that iron deficiency increases growth of the yeast candida in the mouth. This fungal overgrowth can contribute to angular cheilitis, causing redness, dryness and cracking at the corners of the mouth.

Habitual Lip Licking

Some studies have observed that people with iron deficiency have an increased tendency to unconsciously lick their lips. Frequent lip licking can worsen moisture loss and evaporation.

Together, these mechanisms provide plausible explanations for why low iron stores may contribute to problematic dry lips.

Other Causes of Dry Lips

While iron deficiency is one potential cause, many other factors can also produce dry, cracked lips. Common causes include:

Environmental Conditions

Dry air, cold temperatures, and wind can quickly dehydrate lips and remove protective lipids from the skin surface. Low humidity due to indoor heating in the winter often dries out lips.


Certain prescription drugs have drying side effects. Culprits include diuretics, anticholinergics, retinoids, and some blood pressure medications.


Chemicals in tobacco smoke can irritate lips and break down moisture barriers in the skin.

Sun Exposure

Lips have very little melanin, making them prone to sun damage. Prolonged UV radiation exposure takes a toll on the moisture content of lips.


Not drinking enough water can manifest in dry lips. Dehydration reduces fluid levels throughout the body, including the skin.

Atopic Dermatitis

This chronic inflammatory skin condition affects certain areas prone to dryness, including the lips and mouth. It creates redness, cracking, and scaling.

Allergic Reactions

Allergies to foods, skin care products, and substances like pollen can trigger rashes, swelling, and dryness around the mouth.

Vitamin Deficiencies

Deficiencies in vitamins A, B2, B6, B12, C, D, E and zinc have also been associated with dry, cracked lips.


As skin ages, its ability to retain moisture naturally decreases. Fine lines around the lips can exacerbate dryness.

Treatment for Dry Lips from Iron Deficiency

If iron testing reveals a deficiency, addressing the underlying iron levels is key to resolving associated dry lips. However, additional supportive treatments can also help in the short term.

Oral Iron Supplements

Taking iron tablets daily or weekly can help build iron stores back to normal levels. Iron bisglycinate, iron sulfate, iron fumarate, and polysaccharide-iron complex are among the most bioavailable forms. Vitamin C enhances iron absorption.


For those with severe deficiency, intravenous iron infusions can rapidly correct levels. This administration route bypasses potential absorption issues from oral supplements.

Dietary Sources

Including more iron-rich foods can help maintain iron status after treatment:

  • Lean red meat
  • Poultry
  • Seafood
  • Beans
  • Dark leafy greens
  • Dried fruits
  • Iron-fortified cereals

Vitamin C foods can enhance iron absorption from meals. Avoid excessive dairy, tea, coffee, antacids, and calcium at meals as these inhibit iron absorption.

Lip Moisturizers

Frequent use of lip balms and ointments boosts moisture levels while iron levels normalize. Petroleum jelly, shea butter, aloe vera, and natural oils help seal in moisture.


Running a humidifier, especially at night, introduces moisture into the air to prevent excessive evaporation from the lips. This helps combat environmental dryness.

Adequate Hydration

Drinking plenty of water and fluids like herbal tea ensures the body stays well hydrated. Dehydration will exacerbate dry, cracked lips.

Lip Exfoliation

Gently sloughing off flaky, dry skin from the lips allows moisturizers to penetrate better. A soft washcloth, toothbrush, or lip scrub can exfoliate. Avoid harsh scrubbing.

Lip Masks

Intensive leave-on lip masks offer deeper nourishing benefits overnight while you sleep. Look for formulas with hydrating oils, shea or cocoa butter, glycerin, and occlusion agents like petrolatum.

Avoid Irritants

While lips heal, curb exposure to irritants like direct sunlight, wind, tobacco, and food allergens. Don’t pick at dry skin as this can worsen cracks.

Prevention of Dry Lips from Low Iron

Once iron levels normalize, maintaining optimal iron stores can help prevent recurrence of associated dry lips. Strategies include:

  • Eat iron-rich foods regularly, along with vitamin C foods
  • Treat underlying causes of iron deficiency like heavy periods
  • Take iron supplements on occasion, with medical supervision
  • Have iron levels rechecked periodically
  • Use humidifiers during dry weather
  • Stay well hydrated year round
  • Apply lip balm and moisturizer daily
  • Exfoliate and use masks weekly
  • Avoid excessive sun exposure

Iron testing provides the most definitive answer to whether deficiency is causing dry lips. But being aware of risk factors, signs, and prevention tips allows proactive management. Restoring iron levels while providing lip moisture and protection are the keys to resolving this issue.


Dry, cracked lips can certainly occur as a result of iron deficiency or anemia. When the body is low in iron, it seems to manifest in skin dryness and cracking around the mouth. Reduced circulation, inflammation, yeast overgrowth, and lip licking likely all contribute to the development of this symptom. However, many other factors unrelated to iron also commonly cause chapped lips. Only blood testing can determine if iron levels are abnormally low. If iron deficiency is found, treatment aims to increase iron intake through diet or supplements while providing external lip moisture. Managing the underlying deficiency paired with lip hydration offers the best chance of restoring smooth, comfortable lips. With vigilant prevention methods, the recurrence of lip dryness related to low iron can often be avoided.